Sunday, May 17, 2020

Skin Stem Cells - Free Essay Example

Sample details Pages: 2 Words: 673 Downloads: 3 Date added: 2019/06/13 Category Biology Essay Level High school Tags: Stem Cell Essay Did you like this example? Adult stem cells are the undifferentiated cells that are involved in the maintenance, renewal, and repair of various tissues and organs. These stem cells are found in particular niche in a tissue or an organ where they remain undifferentiated and are activated to undergo division and differentiation to maintain the tissue or when activated by disease or disruption. Skin undergoes constant renewal and it is crucial to study the dynamic pathways and key regulators involved at the transcriptional level in proliferation and differentiation of adult stem cells. Don’t waste time! Our writers will create an original "Skin Stem Cells" essay for you Create order In Skin, there are different adult stem cells are located in various locations and can be isolated based on their unique cell surface marker expression. Like epithelium, hair follicles also undergo constant regeneration and have a niche for adult stem cells in the bulge region. Bulge stem cells have shown to regenerate various cell types of the epidermis and when grown in vitro to have shown high proliferation and large colony formation in vitro [1]. The keratinocytes isolated also have shown to be accumulating mutations to form malignant cancers. Skin cancer is one of the most prevalent cancers in United States with around 5 million people being diagnosed and an average of 8 billion dollars is spent on the treatment for skin cancer annually. The statistics on the financial burden on skin cancer and the increasing cases of melanoma and non-melanoma cases detected each year shows the need for research and understanding the underlying mechanisms to prevent skin cancer [2]. As these adult stem cells have such unique characteristics, it is important to know about the key regulators involved in the cell proliferation, cell differentiation, immunity and pathways that lead the cells to become cancerous. Apart from the above tissue specific properties there is also a huge interest in trying to understand universal adult stem cells property and their involvement in cancer. With advances in high throughput sequencing, we are now able to study differential gene expression across various cells and tissues. Deeper sequencing techniques have enabled to sequence the major chunk of the genome which is non-coding transcriptome. RNA-sequencing has made it easy to compare gene expression profiles across samples and in-between two cell types from the same tissue and gives an insight into gene expression, tissue pattern or cell specificity of both protein coding genes and non-coding genes. Having this data will help us understand the key regulators which participate in s tem cell proliferation, differentiation and in our study, genes involved in high colony formation. By isolating specific stem cells from mouse model, it will help us design an experimental model which will allow us to compare the data with publicly available data bases to understand the roles and functions of key regulators involved. Among the non-coding RNAs, long non-coding (lncRNA) RNAs have shown to be involved in regulation, stem cell differentiation and tumor promotion. With increasing evidences of lncRNAs involvement in gene regulation, we decided to look into them and how they are differentially expressed and affect the nearby protein coding genes in our cells of interest from the C57BL6 mouse. LncRNAs are more than 200 bp in length and are involved in gene regulation at transcriptional and post-translational level. They bind with proteins, transcription factors and by binding with other ncRNA alter gene expression. It is also known that lncRNA are tissue specific and are differentially expressed in higher numbers compared with protein-coding genes [3]. In databases like Gencode, they have reported a total of 28468 lncRNA genes in human and 17855 lncRNA genes in mouse [4]. Most of the functions of lncRNAs are still unknown. Identifying differentially expressed genes will be the first step to look into imp ortant genes and pathways that regulate the stem cell characteristics of hair bulge cells compared to the nearby non-stem cell population. To understand better how Long non-coding and mRNA work in the skin we are including parameters like the location of lncRNA and gene expression pattern of selected lncRNA-mRNA across different cancer types to know the function and possible regulatory mechanism of lncRNA on nearby protein-coding genes. Keratinocyte stem cells and cancer

Wednesday, May 6, 2020

Advertising and Society - 2565 Words

Advertising and Society Introduction: Advertising is said to be like glue that holds cultures together. It allows us to share a common experience incorporated by brands, images, logos, and even silly jingles. We define who we are by what we buy and wear because we know that others judge us by what we buy and wear. And advertising influences those judgments. Today because of advertisements conditioning and trendsetting, judgments are made on what clothes people wear, what shampoo and kitchen cleaner they use, not on whom we really are. This leads to a certain degree of social discrimination and emotional insecurity especially in younger population. In advertising, socio-cultural dimensions came in 1920’s. Agencies and publicists no†¦show more content†¦Then he discussed about the role of advertising in developing ideas about the imaginary world. To elaborate his point the author added the analysis by Cronic in 2000.who argued about the imagination of audience and their relationship and said that they cannot be discovered. Moreover he discussed the post modern and cultural critiques of advertising which were based on the modes of consumption. Then he put studies by Matterlart in 1991 and Kenway and Bullen in 2001 which emphasized on the domination of public space and consumption of advertising where as Jameson in 1991 and Baudrilland in 1988 argued about post-modern ways of criticizing advertising. They said that there is a lack of distinction between the real and imaginary world. The main crux of their studies was that advertising creates hyper reality. In order to relate advertising with other different phenomenon’s he discussed about discourse, ideology, myths and representations. According to author there is an interrelationship between discourses, ideologies myths and representations. For discourses he took the example of car advertisement that how they used technology as a discourse in relation to different environments Moreover he added myths as false ideas about consciousness of ideology as in advertisements of beauty products. According to him advertising not only affects our consciousness butShow MoreRelatedAdvertising And Its Effects On Society844 Words   |  4 Pageslogo, and flyers left on windshields as a form of advertising (2011, p.130). According to Medoff and Kaye, advertising serves an educational, social and economic purpose (2011, p.137). Although advertising appears beneficial in many features, it too has its drawbacks and can be similarly unfavorable. Advertising will perhaps become increasingly ubiqui tous, increasingly influential, and increasingly controversial (Advertising, 2011, p.152). Advertising is highly criticized, not so much for its very natureRead MoreAdvertising And Its Effects On Society1167 Words   |  5 PagesCome To Advertising has found ways to be subtle about how they go about demeaning and dehumanizing different genders, races, ages, ethnicities, cultures, and sexual orientations. Society would like to believe that advertising has improved from the days of showing women’s place in the kitchen and only having light skinned models but now advertising companies have just become sneakier and wittier about the way they portray people and the worst part is that society encourages it. Society, as a wholeRead MoreEffect Of Advertising On Society Essay1728 Words   |  7 PagesTalking about advertising, on the one hand, it is good for its functions, displays, etc.; on the other hand, sometimes it is too good to be true, the way they bring the messages to the consumers which state â€Å"the number one †¦Ã¢â‚¬ . What truly are the miscommunications and how do the viewers react to different types of stimulation among those, are there negative or positive results? This review of literature scope was led by the following question: When it comes to communication and advertising are there positiveRead MoreAdvertising And Its Effect On Society1442 Words   |  6 Pagesproduct. Although sometimes advertising can be quite annoying, it can also help in persuading you to buy a product or service. You may be looking for a specific product for a specific purpose or maybe you have heard of a product simply through its exemplary advertising. There are different viewpoints to advertising and many different ways that it appeals and relates to us as individuals and as a society. Today, in order for the advertisements to stay true to their advertising, there has been a set ofRead MoreDeception in Advertising to the Society865 Words   |  3 Pagesthe end. Society considers deception as a relational transgression, which normally leads to betrayal and mistrust among individuals. Deception can take many forms that may include propaganda, dissimulation, distraction, concealment, camou flage and even self-deception (Carson, 2010). Advertising and Deception The most common form of deception is the use of misleading or false statements in commercial transactions. This is referred to as deceptive or false advertising. False advertising is any promotionRead MoreAdvertising And Its Impact On Society1178 Words   |  5 Pagescomes to advertising these differences are not put aside, especially in terms of gender and race. According to Schroeder Borgerson (1998), advertising is quite significant when influencing, building and illustrating consumers vision of the good life, which includes sexual attraction. Domzal Kernan (1993), added that, advertising images represent an essential part of the experienced visual world. Reality and advertising are notRead MoreAdvertising Impact on Society 1190 Words   |  5 PagesAdvertising’s impact on Society Marshall McLuhan, a Canadian philosopher of communication theory said, â€Å"Advertising is the greatest art form of the 20th century.† Like many works of art, advertising is constantly pushing the limits of what is appropriate. It is hard to escape the constant bombardment of advertisements; they are all around us and they have an impact on our cultural values as a society. Industries take full advantage of this constant exposure in order to sell their products, so asRead MoreAdvertising in our Society 555 Words   |  2 PagesAdvertising is the process of communication where a person or groups of people are persuaded to take some form of action, usually to make a purchase or participate in a particular behavior. Advertisements are used in hopes to increase the number of people that use their products or services. All product advertisements try to make people buy their products, so they manipulate facts about the product to make it more appealing to the consumer. Advertiseme nts have such a high level of advertising aroundRead MoreThe Effect Of Advertising On Society1911 Words   |  8 Pagespromotions as they see it as an essential tool in an increasingly capitalistic free market to fuel economic growth. Unfortunately, the surge of unchecked advertising has lead to some adverse effects on societies whether they be moral or ethical in nature. The SAFRA gym advertisement, is an impeccable example of the adverse effects of advertising in today’s society. The advertisement depicts a lean woman who is wearing purple tank top and tight black leggings working out uncomfortably, as two men watched herRead MoreThe Effects Of Advertising On The Society936 Words   |  4 Pagesmarket; conversely competition can go too far or form into something entirely different. In addition, some companies will do anything to boost sales even if that means sacrificing common etiquette or logic to the masses and against their rivals. Advertising is always evolving and a dapting, and for now companies and their advertisers through their advertisements are appearing more cynical and critical by the day. Competition has been a motivating force since man was created. It is a driving pressure

Description of a Religious Festival free essay sample

Write an essay describing a religious festival you celebrated, mentioning what you saw and did in the festival Religion is a â€Å"collective conscience†, a shared outlook created by ceremonies. Most common religion in India is Hinduism. Hindus celebrate thousands of events every year and each in a similar manner, including chanting prayers to the gods and making sweets. Ram Navmi is also one of the event celebrated Hindus. This occasion has great momentousness therefore it’s a nationwide holiday. It is celebrated two days after the seven navratras. Navratras are the days of ‘pooja’ in which Goddess Durga is worshipped by the people for bringing peace and prosperity in their life. People especially ladies keep fast for the first eight days and open on the ninth day. Goddess Durga have nine different incarnations, worshipped one each day. Havans are done, which is also believed by the people that it’s smoke purify the homes. We will write a custom essay sample on Description of a Religious Festival or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page On the ninth day a bigger ‘havan’ is done and then ladies in the family prepare meals for seven young girls and one boy. These girls are treated with respect as they are considered the different forms of Goddess Durga. They are also given offerings in the form of cash. We also celebrate Ram Navmi and so my mother kept a fast for two days. We could not do havan on the first eight days due to lack of space but on the ninth day we had a ‘pandal’ built, made up of tent cloth which was all red in colour which was to give the event its effect supported by thin logs. A pandit was called to conduct the rights and rituals and my mother prepared food for the girls. The eighth day was hectic for me bit I enjoyed it . my sister and I prepared the invitations cards for the children. They had a silver colored fringe with text in golden and a picture of Lord Ganesha with red background. I went to each one’s house to invite them. I also went to buy eight gifts and keeping in mind their ages I found all the appropriate gifts. Then came the ninth day, I was woke up from my sleep by the ‘shank’ sound. I took my bath and got ready for the function. The ‘havan’ started and gradually the girls also came and there was deluge of tasks poured upon me. I had to bring the bucket full of water to wash the ‘kanyas’ feet. Then I went to help the pandit with ‘ghee’,’yoghurt’, etc.

Monday, April 20, 2020

Ovarian Cancer Essays (1205 words) - RTT, Ovarian Cancer

Ovarian Cancer Ovarian cancer is a cancer which forms in the ovaries of a female reproductive organs. Most times it is undetected until small tumors line the abdominal cavity and the cancer cells invade vital organs. This cancer, which is the fifth leading cause of cancer death among American women, has recently shown signs that it may have more success with new treatments for all stages of the disease. Symptoms Ovarian cancer has often times been known as the "silent killer" of American women, but scientists have recently uncovered startling facts: more than 90% of ovarian cancer patients had symptoms of the disease long before it was officially diagnosed. As well as this amazing fact, one in 17 women who live to be 80 will develop ovarian cancer. Some symptoms of this disease include abdominal swelling; digestive disturbances, which include gas, bloating, chronic stomach pains, or indigestion; pelvic pressure; a persistent need to urinate; unexplained weight loss or pain in the pelvis, lower back, or legs. As it can be seen, these symptoms can pertain to many other illnesses, therefore it is hard for a doctor to know ovarian cancer exists. Most times, when these symptoms do not respond to the usual treatments, doctors are instructed to consider ovarian cancer as the problem. Diagnosis, Surgery, and Therapy In order to make a diagnosis, first the doctor requires a thorough medical history of the patient and a pelvic exam, which allows the doctor to feel for abnormalities in the ovaries. If an abnormality is suspected, an ultrasound is usually performed. Usually, for an ultrasound, a probe is placed in the Vagina to gain a clear image of the ovaries. The ultrasound can determine the health of the ovaries and distinguish any more possibilities of the existence of ovarian cancer. To have a better idea of what's wrong with the patient, the doctor obtains a blood test on the patient to measure CA-125. CA-125 is a protein produced by ovarian cancer cells. In advanced ovarian cancer, the protein is elevated in more than 80% of women. In those patients with early-stage cancers, the protein is elevated in more than 50%. Unfortunately, this tool is not perfect. Sometimes these protein levels can also be higher during ovulation or endometriosis. The only certain way to find out if ovarian cancer lives in the patient is to have surgery. During the surgery, the ovaries and other organs of the abdomen are thoroughly inspected. If cancer is strongly suspected, the incision for the surgery is made through the abdomen. The first stage of ovarian cancer is referred to as stage I. This stage is when the cancer is only located in the ovaries. Stage II is classified to the ovaries and other pelvic organs. Stage III is cancer in all the abdominal organs except for the liver, and stage IV includes the liver and other vital organs. Advanced cases are considered the stages from II to IV. Sometimes in the early stages of ovarian cancer, a woman can still conceive, because only one ovary will be removed. If the stage of cancer is very advanced, both ovaries will be removed, as well as the uterus, fallopian tubes, and the momentum. Chemotherapy usually makes CA-125 return to their normal levels. If it remains high or rises during therapy, the cancer may have reoccurred. Some studies suggest that if the tumors return within six months of therapy, the cancer cells could be resistant to drug treatment. A woman visits her physician every few months after her surgery and treatment to keep an eye on her CA-125 levels. Several organizations are trying to develop cancer vaccines targeted at certain cancer-causing proteins, like CA-125. By killing these proteins, they have less of a chance of causing the cancer. Side Effects Chemotherapy drugs kill cancer cells but also damage some normal cells. Temporary side effects might include nausea and vomiting, loss of appetite, loss of hair, mouth and vaginal sores, and changes in the menstrual cycle. Because chemotherapy can damage the blood-producing cells of the bone marrow, patients may have low blood cell counts. This can result in an increased chance of infection, bleeding or bruising after minor cuts or injuries, and fatigue. Potentially permanent side effects include premature menopause and infertility. After radiation therapy,

Sunday, March 15, 2020

Free Essays on Gatsby and the Frozen Moment

In today’s society, it is very easy to look around and see many people who live in their past. Walking down a street, one can still watch cars pass by with peace signs and equal rights slogans or hear blasting disco music from the 70’s. However, although the people in these cars enjoy the culture of the past, they know that it is behind them and can never fully be revived. They know that no matter how much they want the 60’s or the 70’s back, it can never happen, because times have changed. Unfortunately, Gatsby, in the book that bears his name, believed that despite all of the time that had passed and things that had occurred during his five years absence from Daisy, all could be revived. Therefore, he set out to reclaim his love, Daisy, and continue his life, as it had been in the past, unconcerned by all of the changes that had transpired. When Gatsby returned from his service in the armed forces, he embarked on a journey to reclaim his lost sweetheart, Daisy. He found her living in East Egg, married to a man named Tom Buchanan. He, in his obsessive love for Daisy, bought a house in West Egg directly across from hers. He would make extravagant parties with food and liquor, even though he did not drink, just hoping that one day the object of his desire would show up. He just wanted to regain that feeling that emotion that he had for Daisy. The one that he discovered back when he sat with her for hours just staring into her eyes and talking. He just wanted to relive that moment. Finally, after Gatsby met Jordan and Jordan convinced Nick to invite Daisy over, he had his chance. He sat with her again and tried to make everything as it was. He tried to recreate that magic moment in which he knew she was for him. She even led the reader to believe that her life with Tom was over and that she was going to join Gatsby in his world of the past. She chose Gatsby to ride in the car with, she made frequent visits to ... Free Essays on Gatsby and the Frozen Moment Free Essays on Gatsby and the Frozen Moment In today’s society, it is very easy to look around and see many people who live in their past. Walking down a street, one can still watch cars pass by with peace signs and equal rights slogans or hear blasting disco music from the 70’s. However, although the people in these cars enjoy the culture of the past, they know that it is behind them and can never fully be revived. They know that no matter how much they want the 60’s or the 70’s back, it can never happen, because times have changed. Unfortunately, Gatsby, in the book that bears his name, believed that despite all of the time that had passed and things that had occurred during his five years absence from Daisy, all could be revived. Therefore, he set out to reclaim his love, Daisy, and continue his life, as it had been in the past, unconcerned by all of the changes that had transpired. When Gatsby returned from his service in the armed forces, he embarked on a journey to reclaim his lost sweetheart, Daisy. He found her living in East Egg, married to a man named Tom Buchanan. He, in his obsessive love for Daisy, bought a house in West Egg directly across from hers. He would make extravagant parties with food and liquor, even though he did not drink, just hoping that one day the object of his desire would show up. He just wanted to regain that feeling that emotion that he had for Daisy. The one that he discovered back when he sat with her for hours just staring into her eyes and talking. He just wanted to relive that moment. Finally, after Gatsby met Jordan and Jordan convinced Nick to invite Daisy over, he had his chance. He sat with her again and tried to make everything as it was. He tried to recreate that magic moment in which he knew she was for him. She even led the reader to believe that her life with Tom was over and that she was going to join Gatsby in his world of the past. She chose Gatsby to ride in the car with, she made frequent visits to ...

Friday, February 28, 2020

'HOW THE ASSISTANT PRACTITIONER SHOULD ACT TO RESPECT THE PATIENT OR Essay

'HOW THE ASSISTANT PRACTITIONER SHOULD ACT TO RESPECT THE PATIENT OR CLIENT AS AN INDIVIDUAL AND ALWAYS ACT IN THEIR BEST INTEREST' - Essay Example The assistant practitioner works along with qualified team support that is involved in managing and coordinating activities to carry forward health care. The authority is required to undertake certain physiological measures and observations, and then propose a remedial action accordingly. The assistant practitioner is also required to provide teaching and learning assistance to subordinates. It is also part of the assistant practitioner to undertake clinical review processes as per conditions and requirements. The practitioner under his/her capacity is further urged to assist and support the relevant staff during their development phase. The practitioners are required to abide by the Trust core standards and procedures, the staffs are further responsible for their personal awareness related to clinical and personal development. The practitioners are provided with an option to adopt and apply new technique of practice depending upon the circumstances and relevant practices. The practi tioners are urged to review professional clinical supervision to further enhance and improve their clinical practice. It is the responsibility of the practitioner to promote a healthy lifestyle in an active manner, and contribute towards the service development under limited capacity. The practitioners on the basis of their experience have the authority to participate and involve in the recruitment and retention process of their group. The practitioners are provided with an opportunity to undertake therapeutic activities, and if required should also undertake nursing procedures, after seeking relevance guidance and supervision of the registered professional in the clinical setup. It is mandatory upon the practitioner to guarantee safe and healthy environment to the patients, visitors and staff, the practitioners should be aware about the health and safety policies. The

Wednesday, February 12, 2020

Week 2 Coursework Example | Topics and Well Written Essays - 250 words

Week 2 - Coursework Example In this regard, comparative analysis of existing circumstance may influence the decision of an individual when it comes to ethics. In this respect, informed judgment must always be made by an individual to achieve the maximum results on the grounds of ethical expectations. When one is entangled in a situation where a difficult situation has to be made, exceptions on absolute ethical standards are always inevitable (Finser, 2003). There are various incidents that justifies disregard to absolute ethical standards. The motive may sometime justify an action and hence support deviation from absolute ethical standards. Take the instance where one plots to steal cakes to feed a starving family. Absolute ethical approach would consider this action as a wrong but the prevailing circumstance and motives turns out right. In this regard, the situation should be an exception of ethical absolutism. Another situation where the absolute ethical standard may disregarded is where one person is to be killed in an attempt to save several others. For instance, a driver who finds himself in a dilemma situation with a pedestrian to avoid hitting in an incident of brake failure while carrying several people may resort to running over the one pedestrian to save the mass. Although killing is wrong, acting in favor of the mass is ethically justified Finser, 2003). The examples and supportive facts discussed shows need to disobey absolute ethical standards in some